Is COOLIEF* Cooled Radiofrequency the right option for me?

You may not be ready for surgery yet, and opioids have side effects that you might not want. That’s why COOLIEF* can bring non-surgical relief to those suffering from chronic pain, without the use of opioids.1-4

COOLIEF* is a minimally invasive treatment option targeting nerves that transmit pain signals and the first and only radiofrequency treatment FDA-cleared for the relief of osteoarthritis knee pain.5

The top 6 ways COOLIEF* cooled radiofrequency ablation can help with chronic pain

1. Pain relief for up to 12 months

In clinical studies, most patients receiving COOLIEF* reported that their pain was significantly reduced.5

2. Improved mobility

COOLIEF* has been proven to significantly improve long-term physical function and quality of life for OA knee patients for up to 12 months.

3. Quick recovery time

Because the procedure is minimally invasive, most patients can expect to feel pain relief within 1-2 weeks, returning to an enhanced quality of life much sooner than with surgery.

4. No opioid recovery medication

You may experience some discomfort for a short period, but this discomfort can be treated with common over-the-counter medication.6

5. No overnight hospital stay

Since this outpatient treatment requires no general anesthesia, you can return home shortly after treatment.

6. No incision

Unlike surgery, COOLIEF* involves no incision.


2/3 of patients cut

2/3 of COOLIEF patients cut pain in half

in half

83% reduction in severe arthritis

reduction in patients experiencing symptoms of severe arthritis

In a recent clinical study comparing the effectiveness of COOLIEF* Cooled RF vs intra-articular steroid injections to treat OA knee pain, COOLIEF* was found to provide significantly greater and long-lasting pain relief, improved physical function, and higher patient satisfaction than steroid injections.

How the COOLIEF* procedure works

Radiofrequency ablation deactivates the nerves responsible for sending pain signals to the brain.7 COOLIEF* is the only currently known radiofrequency pain management system using water-cooled technology to safely deactivate pain-transmitting sensory nerves, allowing a larger treatment area and greater chance at targeting pain-causing nerves.7 COOLIEF* is clinically proven to provide long-term pain relief, improve physical functionality, and reduce drug utilization.3,8

COOLIEF* probe
Why current chronic pain management options might not work for me
An invasive and expensive path to pain relief

Surgery can be beneficial in properly selected patients. However, due to BMI, age, other comorbidities, or invasiveness, surgery may not be an option for everyone.9,10

An old way of thinking about pain relief

Pain relief has long relied on a daily regimen of prescription medication and over-the-counter pharmaceutical treatments, yet these don’t effectively target nerves that transmit pain and may be associated with11:

Possible opioid side effects
Nausea or vomiting Potentially slower recovery Worsening pain and functionality Potential addiction or dependency
Nausea or vomiting Potentially slower recovery
Worsening pain and functionality Potential addiction or dependency

Opioid prescriptions are often given to patients as a first-line treatment for both acute and chronic pain, although long-term effectiveness has not been proven. In fact, several studies have shown that use of opioids for chronic pain may actually worsen pain and functionality.

Success stories of COOLIEF* treatment 
You may be eligible for COOLIEF* if:

Your pain has lasted for at least 3 months

You are not finding relief or want another option besides pills

You are not a candidate for or aren’t ready for surgery yet

Find a specialist

There are COOLIEF*-trained specialists all across the country. Interested in an appointment?

I’m looking for a COOLIEF*-trained specialist for my     pain near    

More questions?
  1. Malik A, Simopolous T, Elkersh M, et al. Percutaneous radiofrequency lesioning of sensory branches of the obturator and femoral nerves for the treatment of non-operable hip pain. Pain Physician. 2003;6:499-502.
  2. Kawaguchi M, Hashizume K, Iwata T, et al. Percutaneous radiofrequency lesioning of sensory branches of the obturator and femoral nerves for the treatment of hip joint pain. Reg Anesth Pain Med. 2001;26:576-581.
  3. Stelzer W, Aiglesberger M, Stelzer D, Stelzer V. Use of radiofrequency lateral branch neurotomy for the treatment of sacroiliac joint-mediated low back pain: a large case series. Pain Med. 2013;14:29-35.
  4. Rivera F, Mariconda C, Annaratone G. Percutaneous radiofrequency denervation in patients with contraindications for total hip arthoplasty. Orthopedics. 2012;35:e302-e305.
  5. Halyard Health Inc. sponsored study. A prospective, multi-center, randomized, clinical trial evaluating the safety and effectiveness of using COOLIEF Cooled Radiofrequency probe to create lesions of the genicular nerves and comparing corticosteroid steroid in the management of knee pain. Final results 03April2017. Study available upon request from Halyard.
  6. Bogduk N. Practice Guidelines for Spinal Diagnostic and Treatment Procedures. 1st ed. San Francisco, CA: International Spine Intervention Society; 2004.
  7. Kapural L, Nageeb F, Kapural M, et al. Cooled radiofrequency (RF) system for the treatment of chronic pain from sacroiliitis: the first case-series. Pain Pract. 2008;8:348-354.
  8. Ho KY, Hadi MA, Pasutharnchat K, Tan KH. Cooled radiofrequency denervation for treatment of sacroiliac joint pain: two-year results from 20 cases. J Pain Res. 2013;6:505-511.
  9. Choi WJ, Hwang SJ, Song JG, et al. Radiofrequency treatment relieves chronic knee osteoarthritis pain: a double-blind randomized controlled trial. Pain. 2011;152:481-487.
  10. Ikeuchi M, Ushida T, Izumi M, Tani T. Percutaneous radiofrequency treatment for refractory anteromedial pain of osteoarthritic knees. Pain Med. 2011;12:546-551.
  11. American Academy of Orthopaedic Surgeons. Information Statement 1045: Opioid Use, Misuse, and Abuse in Orthopaedic Practice. October 2015.